CNC.IBILI

Therapy7 | Main Goals

Considering the track record of the group integrated members, the focus for the 2015/2020 period will be based on the screening and characterization of bioactive molecules from natural and synthetic sources, using a quick and inexpensive forecast of the potential of new drug candidates combining in silico and in vitro approaches. Afterwards, the relevant information obtained from in silico/in vitro tools will be confirmed by specific studies conducted in non-clinical in vivo models, whose extrapolation to man provides greater accuracy. In particular, it is crucial to predict in the early stages of drug discovery and development the biodisposition (bioavailability, kinetic and dynamic profiles) of the new drug candidates for multiple diseases, and their potential to participate in drug-drug, herb-drug and food-drug interactions with clinical significance.