Metab1 | Structure

The Cell Metabolism and Quality Control Group is an enthusiastic team of more than 50 elements led by Paula I. Moreira. The group leader is an outstanding scientist, as attested by the more than 130 publications and an h-factor of 43 (Google scholar) / 35 (Web of Knowledge). More importantly, Paula I Moreira has a vast experience in the coordination of a research group with a multidisciplinary approach, integrating members in different stages of academic and scientific career. This Group holds members from CNC, IBILI and Coimbra Hospital and University Centre (CHUC), with different but complementary expertise (biochemists, biologists, pharmacists, and clinicians), which provides a more holistic approach to advance understanding of the mechanistic basis of ageing and age-related diseases (e.g. age-related neurodegenerative diseases, diabetes and cardiovascular disease) and accelerate the transfer of knowledge from the bench to the bedside. Each senior scientist will keep an independent research line, within the strategic scientific plan defined for the Group, promoting/privileging collaborative research projects and supervision of MSc and PhD students. The Group team will share laboratory space (two laboratories) maximizing the technical resources available.

Given the unique scientific and technical expertise gathered by the team in the last years, namely in the context of metabolic alterations involving mitochondria and quality control systems, particularly in brain disorders, the team is in a privileged position to collaborate and actively contribute to the development of scientific projects/tasks included in the Thematic Strands “Metabolism, Ageing and Disease” and “Neurosciences, Vision and Disease”.

The Group members will meet on a weekly basis to discuss new ideas, methodologies, results and seminal papers in this field of research. The PIs will have monthly meetings to discuss funding opportunities and the organization of advanced courses, scientific meetings and seminars. The Cell Metabolism and Quality Control Group has several national and international collaborations that improve cooperative ideas and brainstorming, the quality of research and publications and the success rates of funding. The aforementioned and the Group policy to carry out collaborative students’ supervision and research are crucial to progress to high impact publications. The Group also provides learning opportunities and an attractive work environment for undergraduate and graduate students. Some Group members are also actively involved in the dissemination of research findings to the general public.